Extremely preterm birth and autistic traits in young adulthood: the EPICure study

A high prevalence of autism spectrum disorder is reported in children born extremely preterm (EP), but an even larger proportion of survivors are affected by subclinical difficulties than meet diagnostic criteria. The aims of this study were to investigate autistic traits associated with the broader autism phenotype in a cohort of young adults born EP, and explore how these traits relate to emotion recognition, empathy and autism symptom presentation in childhood. The prevalence of autism diagnoses was also investigated.

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Health-Related Quality of Life from Adolescence to Adulthood Following Extremely Preterm Birth

Objective

To examine self-reported and parent-reported health-related quality of life (HRQL) in adults born extremely preterm compared with control participants born at term and to evaluate trajectories of health status from adolescence to early adulthood.

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Preterm birth: Educational and mental health outcomes

Preterm birth (birth at less than 37 weeks’ gestation) is common and represents a major contributor to global child morbidity and mortality.

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Peer Relationship Trajectories in Very Preterm and Term Individuals from Childhood to Early Adulthood

To identify trajectories of peer relationships in very preterm and term-born individuals from 6 to 26 years of age and test early-life predictors of these trajectories.

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Subjective Well-Being and Self-Esteem in Preterm Born Adolescents

An Individual Participant Data Meta-Analysis

To study self-reported well-being and self-esteem among adolescents born very preterm (VPT; <32 wk of gestation) and moderate to late preterm (MLPT; 32–36 wk of gestation) compared with those born full-term (FT) in an individual participant data (IPD) meta-analysis.

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Increased Brain Age Gap Estimate (BrainAGE) in Young Adults After Premature Birth

Recent evidence suggests increased metabolic and physiologic aging rates in premature-born adults. While the lasting consequences of premature birth on human brain development are known, its impact on brain aging remains unclear.

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Decreased amygdala volume in adults after premature birth

Premature-born infants have impaired amygdala structure, presumably due to increased stress levels of premature birth mediated by the amygdala.

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Physical Activity, Mental Health, and Well-Being in Very Pre-Term and Term Born Adolescents: An Individual Participant Data Meta-Analysis of Two Accelerometry Studies

This study examined whether physical activity is associated with better mental health and well-being among very preterm (≤32 weeks) and term born (≥37 weeks) adolescents alike or whether the associations are stronger in either of the groups.

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No change in neurodevelopment at 11 years after extremely preterm birth

Objective To determine whether improvements in school age outcomes had occurred between two cohorts of births at 22–25 weeks of gestation to women residents in England in 1995 and 2006.

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