Decreased BOLD Fluctuations in lateral temporal cortices

Abstract:

Lasting volume reductions in subcortical and temporal-insular cortices after premature birth suggest altered ongoing activity in these areas. We hypothesized altered fluctuations in ongoing neural excitability and activity, as measured by slowly fluctuating blood oxygenation of resting-state functional MRI (rs-fMRI), in premature born adults, with altered fluctuations being linked with underlying brain volume reductions.

A trajectories of behavior, attention, social and emotional problems from childhood to early adulthood following extremely preterm birth: a prospective cohort study

Abstract

To investigate trajectories of behavior, attention, social and emotional problems to early adulthood in extremely preterm survivors compared to a term-born comparison group. Longitudinal analysis of a prospective, population-based cohort of 315 surviving infants born < 26 completed weeks of gestation recruited at birth in 1995, from the UK/Republic of Ireland, and a term-born comparison group recruited at age 6. The parent-report Strengths and Difficulties Questionnaire was completed at age 6, 11, 16 and 19 years.

Infant Regulatory Problems, Parenting Quality & Childhood Attention Problems

Highlights
•   This study adds to evidence that early regulatory problems may mark the starting point of a trajectory of dysregulation,

•  Poor parenting quality may further exacerbate poor regulation, leading to later childhood attention problems.

•  The positive effect of good parenting quality on attention problems is reduced when mothers cope with mental health problems.

SRCD 2019 Biennial Meeting

Professor Dieter Wolke invited to talk on ‘Infant regulatory problems and their implications for subsequent development’ at the Society for Research in Child Development (SRCD) 2019 Biennial Meeting in Baltimore, USA – March 2019.