Cognitive trajectories from infancy to early adulthood following birth before 26 weeks of gestation: a prospective, population-based cohort study

What is already known on this topic?

  • The most common neurologic impairment in children born extremely preterm is in cognitive function.
  • Cognitive development has been well described in infancy and early childhood but the trajectory into early adulthood is unknown.

What this study adds?

  • Impaired cognitive function evident in infancy persists into early adulthood among individuals born extremely preterm, with no evidence of substantial recovery or deterioration.
  • Cognitive test scores in infancy and early childhood reflect early adult outcomes.
  • Male sex and moderate/severe neonatal brain injury has an adverse effect on cognitive trajectories in individuals born extremely preterm.

Read more at: http://dx.doi.org/10.1136/archdischild-2017-313414   (Open Access)